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	<title>Kidney Function &#187; Lih-Wen Mau, Jiannong Liu, Yang Qiu, Haifeng Guo, Areef Ishani, Thomas J. Arneson, David T. Gilbertson, Stephan C. Dunning, Allan J. Collins</title>
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	<description>Renal Information</description>
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		<title>Trends in Patient Characteristics and First-Year Medical Costs of Older Incident Hemodialysis Patients, 1995-2005 &#8211; Corrected Proof</title>
		<link>http://kidneyfunction.org/trends-in-patient-characteristics-and-first-year-medical-costs-of-older-incident-hemodialysis-patients-1995-2005-corrected-proof/</link>
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		<pubDate>Mon, 01 Feb 2010 08:00:00 +0000</pubDate>
		<dc:creator>Lih-Wen Mau, Jiannong Liu, Yang Qiu, Haifeng Guo, Areef Ishani, Thomas J. Arneson, David T. Gilbertson, Stephan C. Dunning, Allan J. Collins</dc:creator>
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		<description><![CDATA[Background: Characteristics of patients with chronic kidney disease who survive to end-stage renal disease may change over time, affecting subsequent outcomes and costs. We examined trends in older incident hemodialysis patient characteristics and analyzed first-year post–dialysis therapy initiation medical costs.Study Design: Retrospective cohort study.Setting &#38; Participants: All US incident hemodialysis patients aged ≥67 years at dialysis therapy initiation from January 1, 1995, to December 31, 2005, with Medicare Part A and Part B in the prior 2 years.Predictor: Year of dialysis therapy initiation.Outcomes: Changes in patient characteristics and first-year costs.Measurements: Mean and median values for continuous variables and percentages of categorical variables; first-year total medical costs measured per person per year. Observed costs were adjusted using Medicare Price Indices and patient case-mix.Results: Median age at dialysis therapy initiation increased from 74.9 to 77.0 years from 1995 (n = 19,044) to 2005 (n = 31,796; P &#60; 0.001). Diabetes prevalence increased from 54.2% to 64.1% (P &#60; 0.001). Median estimated glomerular filtration rate increased from 8.0 to 11.2 mL/min/1.73 m2, and median hemoglobin level increased from 9.4 to 10.2 g/dL. Obesity increased from 8.9% to 22.9% (P &#60; 0.001). First-year observed costs increased by 37.9%; however, inflation-adjusted and case-mix-inflation–adjusted costs were stable. Important adjusters for costs are inability to ambulate/transfer, baseline serum albumin level, primary end-stage renal disease cause, comorbid peripheral vascular disease, and baseline hospital days.Limitations: Population aged ≥67 years at dialysis therapy initiation and results may not generalize to the overall hemodialysis population.Conclusions: From 1995 to 2005, incident hemodialysis patients aged ≥67 years became older, sicker, and more obese with significantly increased estimated glomerular filtration rates and hemoglobin levels at dialysis therapy initiation. Increased first-year post–dialysis therapy initiation costs became stable over time after adjustment for price inflation; case-mix-inflation–adjusted costs remained constant, possibly because of mixed changes in patient characteristics.]]></description>
			<content:encoded><![CDATA[<p>Background: Characteristics of patients with chronic kidney disease who survive to end-stage renal disease may change over time, affecting subsequent outcomes and costs. We examined trends in older incident hemodialysis patient characteristics and analyzed first-year post–dialysis therapy initiation medical costs.Study Design: Retrospective cohort study.Setting &#038; Participants: All US incident hemodialysis patients aged ≥67 years at dialysis therapy initiation from January 1, 1995, to December 31, 2005, with Medicare Part A and Part B in the prior 2 years.Predictor: Year of dialysis therapy initiation.Outcomes: Changes in patient characteristics and first-year costs.Measurements: Mean and median values for continuous variables and percentages of categorical variables; first-year total medical costs measured per person per year. Observed costs were adjusted using Medicare Price Indices and patient case-mix.Results: Median age at dialysis therapy initiation increased from 74.9 to 77.0 years from 1995 (n = 19,044) to 2005 (n = 31,796; P < 0.001). Diabetes prevalence increased from 54.2% to 64.1% (P < 0.001). Median estimated glomerular filtration rate increased from 8.0 to 11.2 mL/min/1.73 m2, and median hemoglobin level increased from 9.4 to 10.2 g/dL. Obesity increased from 8.9% to 22.9% (P < 0.001). First-year observed costs increased by 37.9%; however, inflation-adjusted and case-mix-inflation–adjusted costs were stable. Important adjusters for costs are inability to ambulate/transfer, baseline serum albumin level, primary end-stage renal disease cause, comorbid peripheral vascular disease, and baseline hospital days.Limitations: Population aged ≥67 years at dialysis therapy initiation and results may not generalize to the overall hemodialysis population.Conclusions: From 1995 to 2005, incident hemodialysis patients aged ≥67 years became older, sicker, and more obese with significantly increased estimated glomerular filtration rates and hemoglobin levels at dialysis therapy initiation. Increased first-year post–dialysis therapy initiation costs became stable over time after adjustment for price inflation; case-mix-inflation–adjusted costs remained constant, possibly because of mixed changes in patient characteristics.</p>
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