Outcomes of Hemodialysis Patients in a Long-term Care Hospital Setting: A Single-Center Study – Corrected Proof

Charuhas V. Thakar, Margaret Quate-Operacz, Anthony C. Leonard, Mark H. Eckman — Mon, 14 Dec 2009 12:00:00 +0000

Background: Long-term care hospitals (LTCHs) provide intermediary care after an acute-care hospitalization and usually furnish care to patients with complex medical problems. Outcomes of hemodialysis patients admitted to LTCHs, which includes patients with either end-stage renal disease (ESRD) or acute kidney injury (AKI) requiring dialysis therapy, are not known.Study Design: Observational study.Setting & Participants: All consecutive hemodialysis patients admitted to an LTCH.Predictors: Demographic characteristics, comorbid and laboratory variables, ESRD, and AKI status during LTCH stay.Outcomes: Disposition from LTCHs was classified as discharge to home, nursing home, death in LTCH or hospice care, and re-admission to the hospital. In patients with AKI, renal recovery was defined as discontinuation of dialysis therapy before meeting disposition outcomes.Results: 96 of 206 (46.6%) patients had ESRD, whereas 110 of 206 (53.3%) developed AKI requiring dialysis therapy during the acute-care hospitalization. 63 of 206 (31%) were discharged to home, 11 of 206 (5.4%) died or transferred to hospice, 81 of 206 (40%) went to a nursing home, and 49 of 206 (24%) were re-admitted to a hospital; mortality after re-admission was 32%. Older age (OR, 0.96; 95% CI, 0.93-0.98), diabetes mellitus (OR, 0.45; 95% CI, 0.23-0.94), number of re-admissions to the hospital (OR, 0.38; 95% CI, 0.18-0.78), aminoglycoside use (OR, 0.16; 95% CI, 0.04-0.64), and duration of hospitalization before LTCH admission (OR, 0.96; 95% CI, 0.94-0.99) were associated with lower odds of discharge to home. Of 110 patients with AKI requiring dialysis therapy, 30% (33 patients) discontinued dialysis therapy, whereas 70% were deemed to have ESRD on discharge.Limitations: Retrospective observational study.Conclusions: Most dialysis patients at LTCHs are either re-admitted to acute-care hospitals or require nursing home placement. Only 30% of patients with AKI recover sufficiently to discontinue dialysis therapy, whereas 70% are deemed to have ESRD.

Kidney Function » Charuhas V. Thakar, Margaret Quate-Operacz, Anthony C. Leonard, Mark H. Eckman

Outcomes of Hemodialysis Patients in a Long-term Care Hospital Setting: A Single-Center Study – Corrected Proof