Kidney Function

Membranous glomerulonephritis (MGN) is one of the most common causes of nephrotic syndrome in the adult population, characterized by the formation of subepithelial immune complexes in the glomerular capillary wall and associated with heavy proteinuria. MGN is not a single disease entity, but a pattern of injury in the kidney with diverse causes. MGN can be primary/idiopathic (cause unknown) or secondary. Known causes of secondary MGN are described under 4 broad categories: (1) drugs/medications, (2) infections, (3) autoimmune disorders, and (4) malignancy.